Dehydroaripiprazole
Cat. No.：YN320070
| 产品名称: | Dehydroaripiprazole |
| CAS No.: | 129722-25-4 |
| Chemical Name: | OPC 14857; DM 14857; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-2(1H)-quinolinone; |
| Synonyms: | OPC-14857; DM-14857 |
| 分子量: | 446.37 |
| 分子式: | C₂₃H₂₅Cl₂N₃O₂ |
| SMILES: | O=C1NC2=C(C=CC(OCCCCN3CCN(C4=CC=CC(Cl)=C4Cl)CC3)=C2)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dehydroaripiprazole (OPC-14857) 是 Aripiprazole 的活性代谢产物。Aripiprazole 是一种抗精神病药，被 CYP3A4 和 CYP2D6 代谢，主要形成 Dehydroaripiprazole。Dehydroaripiprazole 具有与 Aripiprazole 同等的抗精神病活性。 |
| IC50和靶点: | [{name:"5-HT1A Receptor:4.2 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Zeidan, T.A., et al.: Crystal. Growth. Design., 13, 2036 (2013)
Nagasaka, Y., et al.: Biopharma. Drug. Dispo., 33, 304 (2012)
Chen, X., et al.: J. Med. Chem., 55, 7141 (2012)
