Methylergometrine maleate
Cat. No.：YN320095
| 产品名称: | Methylergometrine maleate |
| CAS No.: | 57432-61-8 |
| Chemical Name: | (8β)-9,10-Didehydro-N-[(1S)-1-(hydroxymethyl)propyl]-6-methyl-ergoline-8-carbox-amide Maleate; N-[α-(Hydroxymethyl)propyl]-D-lysergamide Maleate; Basofortina; Erezin; Metenarin; Methergin; Methergine; Methylergobasine Maleate; Methylergometrine Maleate; |
| Synonyms: | 马来酸甲麦角新碱; Methylergonovine maleate; Ryegonovin; Spametrin F |
| 分子量: | 455.50 |
| 分子式: | C₂₄H₂₉N₃O₆ |
| SMILES: | [H][C@]1(C2=C[C@@H](C(N[C@H](CO)CC)=O)CN1C)CC3=CNC4=C3C2=CC=C4.OC(/C=C\C(O)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Methylergometrine maleate (Methylergonovine maleate) 是一种麦角生物碱，是一种具有血管收缩和子宫收缩作用的 Methysergide 的活性代谢产物。Methylergometrine maleate 是一种有效的，选择性的，具有口服活性的5-HT受体拮抗剂，pA2值为 9.6。Methylergometrine maleate 具有抗偏头痛和多巴胺能活性，可用于预防和控制产后出血。 |
| IC50和靶点: | [{name:"serotonin:9.6 nM (pA2)"}] |
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| Solvent & Solubility: |
Mueller, L., et al.: Headache, 37, 437 (1997)
de Groot, A.N., et al.: Drugs, 56, 523 (1998)
