SB-399885 hydrochloride
Cat. No.:YN320231
CAS No. :402713-81-9
产品名称: | SB-399885 hydrochloride |
CAS No.: | 402713-81-9 |
Chemical Name: | N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)-benzenesulfonamide, monohydrochloride |
Synonyms: | SB399885 |
分子量: | 482.81 |
分子式: | C₁₈H₂₂Cl₃N₃O₄S |
SMILES: | O=S(C1=CC=C(OC)C(N2CCNCC2)=C1)(NC3=CC(Cl)=CC(Cl)=C3OC)=O.[H]Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SB-399885 hydrochloride 是一个5-HT6受体拮抗剂。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Hirst, W.D., Stean, T.O., Rogers, D.C., et al.SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition modelsEur. J. Pharmacol.553(1-3),109-119(2006)
Wesołowska, A., and Nikiforuk, A.Effects of the brain-penetrant and selective 5-HT6 receptor antagonist SB-399885 in animal models of anxiety and depressionNeuropharmacology52(5),1274-1283(2007)