SB 243213
Cat. No.：YN320236
CAS No. ：200940-22-3
| 产品名称: | SB 243213 |
| CAS No.: | 200940-22-3 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 428.41 |
| 分子式: | C₂₂H₁₉F₃N₄O₂ |
| SMILES: | O=C(N1CCC2=C1C=C(C(F)(F)F)C(C)=C2)NC3=CC=C(OC4=CC=CN=C4C)N=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SB 243213 是一种口服有效的，选择性的，高亲和力的5-HT2C受体拮抗剂，对人 5-HT2C受体的pKi为 9.37，pKb为 9.8。SB 243213 对多种神经递质受体、酶和离子通道具有超过 100 倍的选择性。SB 243213 具有改善的抗焦虑特性，有用于精神分裂症和运动障碍的潜力。 |
| IC50和靶点: | [{name:"Human 5-HT2C Receptor:9.37 (pKi)"},{name: "human 5-HT1A Receptor:<5.3 (pKi)"},{name: "human 5-HT1B Receptor:5.5 (pKi)"},{name: "human 5-HT1D Receptor:6.32 (pKi)"},{name: "human 5-HT1E Receptor:<5.4 (pKi)"},{name: "human 5-HT1F Receptor:5.35 (pKi)"},{name: "Human 5-HT2A Receptor:7.01 (pKi)"},{name: "human 5-HT2B Receptor:7.2 (pKi)"},{name: "Human 5-HT6 Receptor:6.5 (pKi)"},{name: "Human 5-HT7 Receptor:5.64 (pKi)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
