SB-200646A
Cat. No.：YN320238
CAS No. ：143797-62-0
| 产品名称: | SB-200646A |
| CAS No.: | 143797-62-0 |
| Chemical Name: | N-(1-methyl-1H-indol-5-yl)-N′-3-pyridinyl-urea, monohydrochloride |
| Synonyms: | |
| 分子量: | 302.76 |
| 分子式: | C₁₅H₁₅ClN₄O |
| SMILES: | O=C(NC1=CC=CN=C1)NC2=CC3=C(N(C)C=C3)C=C2.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SB-200646A 是第一个对5-HT2B/2C的选择性超过 5-HT2A的拮抗剂，5-HT2B，5-HT2C和 5-HT2A的pKi值分别为 7.5、6.9 和 5.2。SB-200646A 具有口服活性，在体内具有电生理和抗焦虑特性。 |
| IC50和靶点: | [{name:"5-HT2B Receptor:7.5 (pKi)"},{name: "5-HT2C Receptor:6.9 (pKi)"},{name: "5-HT2A Receptor:5.2 (pKi)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Kennett, G.A., Wood, M.D., Glen, A., et al.In vivo properties of SB 200646A, a 5-HT2C/2B receptor antagonistBr. J. Pharmacol.111(3),797-802(1994)
