Facinicline hydrochloride
Cat. No.：YN320351
CAS No. ：677305-02-1
| 产品名称: | Facinicline hydrochloride |
| CAS No.: | 677305-02-1 |
| Chemical Name: | |
| Synonyms: | RG3487 hydrochloride |
| 分子量: | 306.79 |
| 分子式: | C₁₅H₁₉ClN₄O |
| SMILES: | [H]Cl.O=C(C1=NNC2=C1C=CC=C2)N[C@@H]3CN4CCC3CC4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Facinicline hydrochloride (RG3487 hydrochloride) 是具有口服活性的烟碱α7 receptor部分激动剂，对人nAChR 的Ki值为 6 nM。Facinicline hydrochloride (RG3487 hydrochloride) 可改善啮齿类动物的认知和感觉运动门控。Facinicline hydrochloride (RG3487 hydrochloride) 对5-HT3受体 (拮抗剂)的Ki值为 1.2 nM。 |
| IC50和靶点: | [{name:"5-HT3 Receptor:1.2 nM (Ki)"},{name: "α7:6 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
