SCH-23390 maleate
Cat. No.：YN320360
| 产品名称: | SCH-23390 maleate |
| CAS No.: | 87134-87-0 |
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| 分子量: | 403.86 |
| 分子式: | C₂₁H₂₂ClNO₅ |
| SMILES: | OC1=C(Cl)C=C2CCN(C)C[C@H](C3=CC=CC=C3)C2=C1.O=C(O)/C=C\C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SCH-23390 maleate (R-(+)-SCH-23390 maleate) 是一种有效的选择性的多巴胺D1样受体拮抗剂，其对D1和D5受体的Ki分别为 0.2 nM 和 0.3 nM。SCH-23390 maleate 也是一种有效的人5-HT2C受体激动剂，Ki为 9.3 nM。SCH-23390 maleate 与5-HT2和5-HT1C受体具有高亲和力。SCH-23390 maleate 还抑制 G 蛋白偶联的内向整流钾 (GIRK) 通道，IC50为 268 nM。 |
| IC50和靶点: | [{name:"D1 Receptor:0.2 nM (Ki)"},{name: "D5 Receptor:0.3 nM (Ki)"},{name: "5-HT2C Receptor:9.3 nM (Ki)"},{name: "GIRK:268 nM (IC50)"}] |
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