LY310762
Cat. No.：YN320748
| 产品名称: | LY310762 |
| CAS No.: | 192927-92-7 |
| Chemical Name: | 1-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-one, monohydrochloride |
| Synonyms: | LY310762 HCl |
| 分子量: | 430.94 |
| 分子式: | C₂₄H₂₈ClFN₂O₂ |
| SMILES: | O=C1N(CCN2CCC(C(C3=CC=C(F)C=C3)=O)CC2)C4=C(C=CC=C4)C1(C)C.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | LY310762是5-HT1D受体拮抗剂，Ki为249 nM，对5-HT1B受体亲和力较弱。 |
| IC50和靶点: | [{name:"5-HT1D Receptor:249 nM (Ki)"}] |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Pullar, I.A., Boot, J.R., Broadmore, R.J., et al.The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pigEur. J. Pharmacol.493(1-3),85-93(2004)
García-Pedraza, J.Á., García, M., Martín, M.L., et al.Pharmacological evidence that 5-HT1D activation induces renal vasodilation by NO pathway in ratsClin. Exp. Pharmacol. Physiol.42(6),640-647(2015)
