Blonanserin
Cat. No.：YN320759
CAS No. ：132810-10-7
| 产品名称: | Blonanserin |
| CAS No.: | 132810-10-7 |
| Chemical Name: | 2-(4-ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydro-cycloocta[b]pyridine |
| Synonyms: | 布南色林; AD-5423 |
| 分子量: | 367.50 |
| 分子式: | C₂₃H₃₀FN₃ |
| SMILES: | FC1=CC=C(C2=C(CCCCCC3)C3=NC(N4CCN(CC)CC4)=C2)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Blonanserin (AD-5423) 是一种有效的5-HT2A(Ki= 0.812 nM) 和多巴胺 D2 受体 (Ki= 0.142 nM) 拮抗剂。Blonanserin 通常作为一种非典型的抗精神病试剂，可用于锥体外系症状、过度镇静或低血压的研究。 |
| IC50和靶点: | [{name:"D2 Receptor:0.142 nM (Ki)"},{name: "D3 Receptor:0.494 nM (Ki)"},{name: "D4 Receptor:150 nM (Ki)"},{name: "D1 Receptor:1070 nM (Ki)"},{name: "5-HT2A Receptor:0.812 nM (Ki)"},{name: "5-HT2C Receptor:26.4 nM (Ki)"},{name: "5-HT6 Receptor:11.7 nM (Ki)"},{name: "α1-adrenergic receptor:26.7 (Rat nM (Ki)"},{name: "α2-adrenergic receptor:530 (Rat c nM (Ki)"}] |
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| Solvent & Solubility: |
Tenjin, T., Miyamoto, S., Ninomiya, Y., et al.Profile of blonanserin for the treatment of schizophreniaNeuropsychiatr. Dis. Treat.9,587-594(2013)
