SEP-363856 hydrochloride
Cat. No.:YN320765
产品名称: | SEP-363856 hydrochloride |
CAS No.: | 1310422-41-3 |
Chemical Name: | 4,7-dihydro-N-methyl-5H-thieno[2,3-c]pyran-7-methanamine, monohydrochloride |
Synonyms: | SEP-856 hydrochloride |
分子量: | 219.73 |
分子式: | C₉H₁₄ClNOS |
SMILES: | CNC[C@H]1C2=C(C=CS2)CCO1.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SEP-363856 (SEP-856) hydrochloride 是具有口服活性的、中枢神经系统活性的抗精神病活性化合物,具有研究精神分裂症的潜力。 |
IC50和靶点: | [{name:"TAAR1:0.140 μM (EC50)"},{name: "5-HT1A Receptor:2.3 μM (EC50)"},{name: "5-HT1B Receptor:15.6 μM (EC50)"},{name: "5-HT1D Receptor:0.262 μM (EC50)"},{name: "5-HT2A Receptor:>10 μM (EC50)"},{name: "5-HT2C Receptor:30 μM (EC50)"},{name: "5-HT7 Receptor:6.7 μM (EC50)"}] |
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Dedic, N., Jones, P.G., Hopkins, S.C., et al.SEP-363856, a novel psychotropic agent with a unique, non-D2 receptor mechanism of actionJ. Pharmacol. Exp. Ther.371(1),1-14(2019)