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SEP-363856 hydrochloride

Cat. No.:YN320765

  • CAS No. :1310422-41-3

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    • 产品名称: SEP-363856 hydrochloride
      CAS No.: 1310422-41-3
      Chemical Name: 4,7-dihydro-N-methyl-5H-thieno[2,3-c]pyran-7-methanamine, monohydrochloride
      Synonyms:SEP-856 hydrochloride
      分子量:219.73
      分子式:C₉H₁₄ClNOS
      SMILES:CNC[C@H]1C2=C(C=CS2)CCO1.Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: SEP-363856 (SEP-856) hydrochloride 是具有口服活性的、中枢神经系统活性的抗精神病活性化合物,具有研究精神分裂症的潜力。
      IC50和靶点: [{name:"TAAR1:0.140 μM (EC50)"},{name: "5-HT1A Receptor:2.3 μM (EC50)"},{name: "5-HT1B Receptor:15.6 μM (EC50)"},{name: "5-HT1D Receptor:0.262 μM (EC50)"},{name: "5-HT2A Receptor:>10 μM (EC50)"},{name: "5-HT2C Receptor:30 μM (EC50)"},{name: "5-HT7 Receptor:6.7 μM (EC50)"}]
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    • Dedic, N., Jones, P.G., Hopkins, S.C., et al.SEP-363856, a novel psychotropic agent with a unique, non-D2 receptor mechanism of actionJ. Pharmacol. Exp. Ther.371(1),1-14(2019)

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