Olanzapine D3
Cat. No.：YN320878
| 产品名称: | Olanzapine D3 |
| CAS No.: | 786686-79-1 |
| Chemical Name: | 2-Methyl-4-(4-methyl-d3-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine; Integrol-d3; LY 170053-d3; Lanzac-d3; Oleanz-d3; Oliza-d3; Oltal-d3; Zyprexa-d3; |
| Synonyms: | 奥氮平 D3; LY170053 D3 |
| 分子量: | 315.45 |
| 分子式: | C₁₇H₁₇D₃N₄S |
| SMILES: | [2H]C(N1CCN(C2=NC3=CC=CC=C3NC4=C2C=C(C)S4)CC1)([2H])[2H] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Olanzapine D3 (LY170053 D3) 是 Olanzapine 的氘代物。Olanzapine 是一种选择性单胺能拮抗剂，高亲和力结合 5-羟色胺H1，5HT2A/2C，5HT3，5HT6(Ki分别为 7、4、11、57 和 5 nM)，多巴胺D1-4(Ki=11-31 nM)，毒蕈碱M1-5(Ki=1.9-25 nM) 和肾上腺素α1受体 (Ki=19 nM)。Olanzapine 是一种非典型的抗精神病剂。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Moore, N.A., et al.: Curr. Opin Invest. Drugs, 2, 281 (1993), Baldwin, D.S. and Montgomery, S.A.: Int. Clin. Psychopharmacol., 10, 239 (1995), Tohen, M., et al.: Am. J. Psychiatry, 156, 702 (1999)
