Aripiprazole
Cat. No.：YN320883
CAS No. ：129722-12-9
| 产品名称: | Aripiprazole |
| CAS No.: | 129722-12-9 |
| Chemical Name: | 7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone |
| Synonyms: | 阿立哌唑; OPC-14597 |
| 分子量: | 448.39 |
| 分子式: | C₂₃H₂₇Cl₂N₃O₂ |
| SMILES: | O=C1NC2=C(C=CC(OCCCCN3CCN(C4=CC=CC(Cl)=C4Cl)CC3)=C2)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Aripiprazole (OPC-14597) 是人5-HT1A受体部分激动剂，Ki 为4.2 nM。 |
| IC50和靶点: | [{name:"5-HT1A Receptor:4.2 nM (Ki)'}, '5-HT2A Receptor', '5-HT2B Receptor', '5-HT2C Receptor', 'D2 Receptor', 'D3 Receptor', 'D4 Receptor'] |
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Shapiro, D.A., Renock, S., Arrington, E., et al.Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacologyNeuropsychopharmacology28(8),1400-1411(2003)
Fejgin, K., Safonov, S., Pålsson, E., et al.The atypical antipsychotic, aripiprazole, blocks phencyclidine-induced disruption of prepulse inhibition in micePsychopharmacology (Berl.)191(2),377-385(2007)
