TG6-10-1
Cat. No.：YN321097
CAS No. ：1415716-58-3
| 产品名称: | TG6-10-1 |
| CAS No.: | 1415716-58-3 |
| Chemical Name: | (2E)-N-[2-[2-(trifluoromethyl)-1H-indol-1-yl]ethyl]-3-(3,4,5-trimethoxyphenyl)-2-propenamide |
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| 分子量: | 448.43 |
| 分子式: | C₂₃H₂₃F₃N₂O₄ |
| SMILES: | O=C(NCCN1C(C(F)(F)F)=CC2=C1C=CC=C2)/C=C/C3=CC(OC)=C(OC)C(OC)=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TG6-10-1 是一种EP2拮抗剂, 低纳摩尔下有效作用于 EP2, 比作用于人 EP3, EP4 和 IP 受体选择性高 300, EP1 受体选择性高 100 倍的。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Jiang, J., Quan, Y., Ganesh, T., et al.Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammationProc. Natl. Acad. Sci. USA110(9),3591-3596(2013)
Rojas, A., Ganesh, T., Lelutiu, N., et al.Inhibition of the prostaglandin EP2 receptor is neuroprotective and accelerates functional recovery in a rat model of organophosphorus induced status epilepticusNeuropharmacology93,15-27(2015)
