Agomelatine hydrochloride
Cat. No.：YN321109
CAS No. ：1176316-99-6
| 产品名称: | Agomelatine hydrochloride |
| CAS No.: | 1176316-99-6 |
| Chemical Name: | |
| Synonyms: | 维度新; S-20098 hydrochloride |
| 分子量: | 279.76 |
| 分子式: | C₁₅H₁₈ClNO₂ |
| SMILES: | CC(NCCC1=C2C=C(OC)C=CC2=CC=C1)=O.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Agomelatine hydrochloride (S-20098 hydrochloride) 是一种MT1和MT2受体的特异性激动剂，对 CHO-hMT1，HEK-hMT1，CHO-hMT2，HEK-hMT2 的Ki分别为 0.1，0.06，0.12 和 0.27 nM。Agomelatine hydrochloride 还是一种选择性的5-HT2C受体拮抗剂，在天然 (猪) 和克隆的人 5-HT2C 受体中pKi分别为 6.4 和 6.2。 |
| IC50和靶点: | [{name:"5-HT2C Receptor:6.4 (pKi, native porcine)"},{name: "5-HT2C Receptor:6.2 (pKi, human)"},{name: "hMT1:0.1 (Ki, CHO Cells)"},{name: "hMT1:0.06 (Ki, HEK Cells)"},{name: "hMT2:0.12 (Ki, CHO Cells)"},{name: "hMT2:0.27 (Ki, HEK Cells)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
