SB-215505
Cat. No.:YN321185
CAS No. :162100-15-4
产品名称: | SB-215505 |
CAS No.: | 162100-15-4 |
Chemical Name: | 6-Chloro-5-methyl-1-(5-quinolylcarbamoyl)indoline; 6-Chloro-2,3-dihydro-5-methyl-N-5-quinolinyl-1H-indole-1-carboxamide; |
Synonyms: | |
分子量: | 337.80 |
分子式: | C₁₉H₁₆ClN₃O |
SMILES: | O=C(N1CCC2=C1C=C(Cl)C(C)=C2)NC3=C4C=CC=NC4=CC=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SB-215505 是一种有效的,亚型选择性5-HT2B受体拮抗剂,对 5-HT2B,5-HT2A,5-HT2C的pKi值分别为 8.3、6.77、7.66。SB-215505 可以增加大鼠的清醒和运动活动。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Fabre, A., et al.: Eur. Respir. J., 32, 426-436 (2008)
Dizeyi, N., et al.: Eur. Urol., 47, 895-900 (2005)