SCH-23390 hydrochloride
Cat. No.：YN321229
CAS No. ：125941-87-9
| 产品名称: | SCH-23390 hydrochloride |
| CAS No.: | 125941-87-9 |
| Chemical Name: | 8-chloro-2,3,4,5-tetrahydro-3-methyl-5R-phenyl-1H-3-benzazepin-7-ol, monohydrochloride |
| Synonyms: | R-(+)-SCH-23390 hydrochloride, SCH-23390 HCl |
| 分子量: | 324.24 |
| 分子式: | C₁₇H₁₉Cl₂NO |
| SMILES: | OC1=C(Cl)C=C2CCN(C)C[C@H](C3=CC=CC=C3)C2=C1.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) 是一种有效的选择性的多巴胺D1样受体拮抗剂，其对D1和D5受体的Ki分别为 0.2 nM 和 0.3 nM。SCH-23390 hydrochloride 也是一种有效的人5-HT2C受体激动剂，Ki为 9.3 nM。SCH-23390 hydrochloride 与5-HT2和5-HT1C受体具有高亲和力。SCH-23390 hydrochloride 还抑制 G 蛋白偶联的内向整流钾 (GI |
| IC50和靶点: | [{name:"D1 Receptor:0.2 nM (Ki)"},{name: "D5 Receptor:0.3 nM (Ki)"},{name: "5-HT2C Receptor:9.3 nM (Ki)"},{name: "GIRK:268 nM (IC50)"}] |
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