Eptapirone
Cat. No.：YN321258
| 产品名称: | Eptapirone |
| CAS No.: | 179756-58-2 |
| Chemical Name: | 4-methyl-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-1,2,4-triazine-3,5(2H,4H)-dione |
| Synonyms: | F 11440 |
| 分子量: | 345.40 |
| 分子式: | C₁₆H₂₃N₇O₂ |
| SMILES: | O=C(N1C)N(CCCCN2CCN(C3=NC=CC=N3)CC2)N=CC1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Eptapirone (F11440) 是一种强效，选择性，疗效高的 5HT1A 受体激动剂, 有显著的抗焦虑和抗抑郁潜力。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Koek, W., Patoiseau, J.-F., Assie, M.-B., et al.F 11440, a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potentialJ.Pharmacol. Exp. Ther.287(1),266-283(1998)
Thomas, G.H., Babbs, A.J., Chatfield, R.E., et al.5-HT1A activation counteracts cardiovascular but not hypophagic effects of sibutramine in ratsObesity (Silver Spring)17(3),467-473(2009)
