Tianeptine sodium salt
Cat. No.：YN321316
CAS No. ：30123-17-2
| 产品名称: | Tianeptine sodium salt |
| CAS No.: | 30123-17-2 |
| Chemical Name: | 7-[(3-chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)amino]-heptanoic acid, monosodium salt |
| Synonyms: | 噻奈普汀钠 |
| 分子量: | 458.93 |
| 分子式: | C₂₁H₂₄ClN₂NaO₄S |
| SMILES: | O=C(CCCCCCNC(C1=CC=CC=C1N2C)C3=CC=C(C=C3S2(=O)=O)Cl)O[Na] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tianeptine sodium salt 是一种选择性5-HT摄取促进剂。Tianeptine sodium salt 对包括 5-HT 和多巴胺 (IC50>10 μM) 在内的多种受体没有亲和力，并且对去甲肾上腺素和多巴胺的吸收没有影响。Tianeptine sodium salt 具有抗抑郁，抗焦虑，镇痛和神经保护作用。 |
| IC50和靶点: | |
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Gassaway, M.M., Rives, M.L., Kruegel, A.C., et al.The atypical antidepressant and neurorestorative agent tianeptine is a μ-opioid receptor agonistTransl. Psychiatry4(7),e411(2014)
Lauhan, R., Hsu, A., Alam, A., et al.Tianeptine abuse and dependence: Case report and literature reviewPsychosomatics59(6),547-553(2018)
McEwen, B.S., Chattarji, S., Diamond, D.M., et al.The neurobiological properties of tianeptine (Stablon): From monoamine hypothesis to glutamatergic modulationMol. Psychiatry15(3),237-249(2010)
