Palonosetron Hydrochloride
Cat. No.：YN321331
| 产品名称: | Palonosetron Hydrochloride |
| CAS No.: | 135729-62-3 |
| Chemical Name: | 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3aS,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one, monohydrochloride |
| Synonyms: | 盐酸帕洛诺司琼 |
| 分子量: | 332.87 |
| 分子式: | C₁₉H₂₅ClN₂O |
| SMILES: | O=C1N(C[C@@]([H])(CCC2)C3=C2C=CC=C13)[C@@H]4CN5CCC4CC5.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Palonosetron盐酸盐是5-HT3拮抗剂，能抑制化疗引起的恶心呕吐（CINV）。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Wong, E.H., Clark, R., Leung, E., et al.The interaction of RS 25259-197, a potent and selective antagonist, with 5-HT3 receptors, in vitroBr. J. Pharmacol.114(4),851-859(1995)
Eglen, R.M., Lee, C.H., Smith, W.L., et al.Pharmacological characterization of RS 25259-197, a novel and selective 5-HT3 receptor antagonist, in vivoBr. J. Pharmacol.114(4),860-866(1995)
