Ondansetron hydrochloride dihydrate
Cat. No.：YN321366
CAS No. ：103639-04-9
| 产品名称: | Ondansetron hydrochloride dihydrate |
| CAS No.: | 103639-04-9 |
| Chemical Name: | 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one, monohydrochloride, dihydrate |
| Synonyms: | GR 38032 hydrochloride dihydrate; SN 307 hydrochloride dihydrate |
| 分子量: | 365.85 |
| 分子式: | C₁₈H₂₄ClN₃O₃ |
| SMILES: | O=C1C(CN2C=CN=C2C)CCC(N3C)=C1C4=C3C=CC=C4.[H]Cl.O.O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ondansetron hydrochloride dihydrate (GR 38032 hydrochloride dihydrate; SN 307 hydrochloride dihydrate) 是5- HT3受体拮抗剂。 |
| IC50和靶点: | |
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Hesketh, P.J.Comparative review of 5-HT3 receptor antagonists in the treatment of acute chemotherapy-induced nausea and vomitingCancer Invest.18(2),163-173(2000)
Johnson, B.A., Roache, J.D., Javors, M.A., et al.Ondansetron for reduction of drinking among biologically predisposed alcoholic patients: A randomized controlled trialJAMA284(8),963-971(2000)
Johnson, B.A., Ait-Daoud, N., Ma, J.Z., et al.Ondansetron reduces mood disturbance among biologically predisposed, alcohol-dependent individualsAlcohol Clin. Exp. Res.27(11),1773-1779(2003)
