Lurasidone Hydrochloride
Cat. No.：YN321376
CAS No. ：367514-88-3
| 产品名称: | Lurasidone Hydrochloride |
| CAS No.: | 367514-88-3 |
| Chemical Name: | (3aR,4S,7R,7aS)-2-[[(1R,2R)-2-[[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione Hydrochloride; Latuda, SM 13496; |
| Synonyms: | 盐酸鲁拉西酮; SM-13496 Hydrochloride |
| 分子量: | 529.14 |
| 分子式: | C₂₈H₃₇ClN₄O₂S |
| SMILES: | O=C([C@H]([C@H]1CC[C@@H]2C1)[C@H]2C3=O)N3C[C@@H]4CCCC[C@H]4CN(CC5)CCN5C6=NSC7=CC=CC=C76.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) 是dopamine D2和5-HT7的拮抗剂，IC50值分别为 1.68 和 0.495 nM。 Lurasidone 也是5-HT1A受体的部分激动剂，IC50值为 6.75 nM。 |
| IC50和靶点: | [{name:"5-HT7 Receptor:0.495 nM (IC50)"},{name: "5-HT1A Receptor:6.75 nM (IC50)"},{name: "D2 Receptor:1.68 nM (IC50)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007), Cole, P., et al.: Drugs of the Fut., 33, 316 (2008),
