Azasetron hydrochloride
Cat. No.：YN321379
CAS No. ：123040-16-4
| 产品名称: | Azasetron hydrochloride |
| CAS No.: | 123040-16-4 |
| Chemical Name: | N-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide, monohydrochloride |
| Synonyms: | 盐酸阿扎司琼; Y-25130 hydrochloride |
| 分子量: | 386.27 |
| 分子式: | C₁₇H₂₁Cl₂N₃O₃ |
| SMILES: | O=C(C1=C(OCC(N2C)=O)C2=CC(Cl)=C1)NC3CN4CCC3CC4.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Azasetron (Y-25130) hydrochloride，是一种苯甲酰胺的衍生物，是有效的、选择性的5-HT3受体拮抗剂。Azasetron 可用于化疗引起的恶心呕吐研究。 |
| IC50和靶点: | [{name:"5-HT3 Receptor:0.33 nM (IC50)"}] |
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| Solvent & Solubility: |
Haga, K., Inaba, K., Shoji, H., et al.The effects of orally administered Y-25130, a selective serotonin3-receptor antagonist, on chemotherapeutic agent-induced emesisJpn. J. Pharmacol.63(3),377-383(1993)
Sato, N., Sakamori, M., Haga, K., et al.Antagonistic activity of Y-25130 on 5-HT3 receptorsJpn. J. Pharmacol.59(4),443-448(1992)
