Pizotifen malate
Cat. No.：YN321392
| 产品名称: | Pizotifen malate |
| CAS No.: | 5189-11-7 |
| Chemical Name: | 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine, 2-hydroxy-butanedioic acid |
| Synonyms: | Pizotyline malate; BC-105 malate |
| 分子量: | 429.53 |
| 分子式: | C₂₃H₂₇NO₅S |
| SMILES: | O=C(O)C(O)CC(O)=O.CN1CC/C(CC1)=C2C3=CC=CC=C3CCC4=C\2C=CS4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pizotifen malate (Pizotyline malate) 是5-HT2受体的有效拮抗剂，并对5-HT1C有高亲和力。 |
| IC50和靶点: | |
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Morimoto, A., Yamada, H., Watanabe, T., et al.Synthesis and structure-activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonistsBioorg. Med. Chem.21(24),7841-7852(2013)
Pringsheim, T., Davenport, W.J., and Becker, W.J.Prophylaxis of migraine headacheCMAJ182(7),(2010)
