Sumatriptan succinate
Cat. No.：YN321393
| 产品名称: | Sumatriptan succinate |
| CAS No.: | 103628-48-4 |
| Chemical Name: | 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide-butanedioic acid |
| Synonyms: | 舒马普坦琥珀酸盐; GR 43175 |
| 分子量: | 413.49 |
| 分子式: | C₁₈H₂₇N₃O₆S |
| SMILES: | O=C(O)CCC(O)=O.O=S(CC1=CC2=C(NC=C2CCN(C)C)C=C1)(NC)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sumatriptan succinate (GR 43175) 是5-HT1受体激动剂，可作用于偏头疼。 |
| IC50和靶点: | [{name:"5-HT1D Receptor:17 nM (Ki)"},{name: "5-HT1B Receptor:27 nM (Ki)"},{name: "5-HT1A Receptor:100 nM (Ki)"}] |
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Razzaque, Z., Heald, M.A., Pickard, J.D., et al.Vasoconstriction in human isolated middle meningeal arteries: Determining the contribution of 5-HT1B- and 5-HT1F-receptor activationBr. J. Pharmacol.47(1),75-82(1999)
Pradhan, A., Smith, M.L., McGuire, B., et al.Characterization of a novel model of chronic migrainePain155(2),269-274(2014)
