Mosapride citrate
Cat. No.：YN321411
| 产品名称: | Mosapride citrate |
| CAS No.: | 112885-42-4 |
| Chemical Name: | 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-benzamide, 2-hydroxy-1,2,3-monopropanetricarboxylate |
| Synonyms: | 莫沙必利柠檬酸盐; TAK-370 citrate; AS-4370 citrate |
| 分子量: | 614.02 |
| 分子式: | C₂₇H₃₃ClFN₃O₁₀ |
| SMILES: | O=C(NCC1CN(CC2=CC=C(F)C=C2)CCO1)C3=CC(Cl)=C(N)C=C3OCC.O=C(CC(C(O)=O)(O)CC(O)=O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mosapride柠檬酸盐是促胃肠动力化合物，是5HT4激动剂。 |
| IC50和靶点: | |
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Yoshida, N., Omoya, H., Oka, M., et al.AS-4370, a novel gastrokinetic agent free of dopamine D2 receptor antagonist propertiesArch. Int. Pharmacodyn. Ther.300,51-67(1989)
Hirokawa, Y., Fujiwara, I., Suzuki, K., et al.Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activityJ. Med. Chem.46(5),702-715(2003)
Mine, Y., Yoshikawa, T., Oku, S., et al.Comparison of effect of mosapride citrate and existing 5-HT4 receptor agonists on gastrointestinal motility in vivo and in vitroJ. Pharmacol. Exp. Ther.283(3),1000-1008(1997)
