Rizatriptan benzoate
Cat. No.：YN321430
| 产品名称: | Rizatriptan benzoate |
| CAS No.: | 145202-66-0 |
| Chemical Name: | N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine, monobenzoate |
| Synonyms: | MK 462 |
| 分子量: | 391.47 |
| 分子式: | C₂₂H₂₅N₅O₂ |
| SMILES: | CN(C)CCC1=CNC2=C1C=C(CN3N=CN=C3)C=C2.O=C(O)C4=CC=CC=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rizatriptan 苯甲酸盐(Maxalt)是 5-HT1激动剂。 |
| IC50和靶点: | |
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Xu, Y.-C., Schaus, J.M., Walker, C., et al.N-Methyl-5-tert-butyltryptamine: A novel, highly potent 5-HT1D receptor agonistJ. Med. Chem.42(3),526-531(1999)
Longmore, J., Razzaque, Z., Shaw, D., et al.Comparison of the vasoconstrictor effects of rizatriptan and sumatriptan in human isolated cranial arteries: Immunohistological demonstration of the involvement of 5-HT1B-receptorsBr. J. Clin. Pharmacol.46(6),577-582(1998)
Chanda, M.L., Tuttle, A.H., Baran, I., et al.Behavioral evidence for photophobia and stress-related ipsilateral head pain in transgenic Cacna1a mutant micePain154(8),1254-1262(2013)
