Urapidil hydrochloride
Cat. No.：YN321459
| 产品名称: | Urapidil hydrochloride |
| CAS No.: | 64887-14-5 |
| Chemical Name: | 6-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione monohydrochloride |
| Synonyms: | 盐酸乌拉地尔 |
| 分子量: | 423.94 |
| 分子式: | C₂₀H₃₀ClN₅O₃ |
| SMILES: | O=C1N(C)C(C=C(NCCCN2CCN(C3=CC=CC=C3OC)CC2)N1C)=O.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Urapidil盐酸盐是α1-肾上腺素受体拮抗剂和5-HT1A受体激动剂。 |
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Gross, G., Hanft, G., and Kolassa, N.Urapidil and some analogues with hypotensive properties show high affinities for 5-hydroxytryptamine (5-HT) binding sites of the 5-HT1A subtype and for α1-adrenoceptor binding sitesNaunyn Schmiedebergs Arch Pharmacol.336(6),597-601(1987)
van Zwieten, P.A.Pharmacologic profile of urapidilAm. J. Cardiol.64(7),1D-6D(1989)
Schoeffter, P., and Hoyer, D.Centrally acting hypotensive agents with affinity for 5-HT1A binding sites inhibit forskolin-stimulated adenylate cyclase activity in calf hippocampusBr. J. Pharmacol.95(3),975-985(1988)
Verberne, A.J., and Rand, M.J.Effect of urapidil on β-adrenoceptors of rat atriaEur. J. Pharmacol.108(2),193-196(1985)
Kolassa, N., Beller, K.D., and Sanders, K.H.Involvement of brain 5-HT1A receptors in the hypotensive response to urapidilAm. J. Cardiol.64(7),7D-10D(1989)
