Chlorpromazine D6 hydrochloride
Cat. No.：YN321486
| 产品名称: | Chlorpromazine D6 hydrochloride |
| CAS No.: | 1228182-46-4 |
| Chemical Name: | 2-chloro-N,N-di(methyl-d3)-10H-phenothiazine-10-propanamine, monohydrochloride |
| Synonyms: | 盐酸氯丙嗪 D6 |
| 分子量: | 361.36 |
| 分子式: | C₁₇H₁₄D₆Cl₂N₂S |
| SMILES: | ClC1=CC=C(SC(C=CC=C2)=C2N3CCCN(C([2H])([2H])[2H])C([2H])([2H])[2H])C3=C1.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Chlorpromazine D6 hydrochloride 是 Chlorpromazine 的氘代物。Chlorpromazine 是 dopamine 受体，5-HT 受体，potassium channel，sodium channel 的拮抗剂。 |
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Seeman, P., and Tallerico, T.Antipsychotic drugs which elicit little or no Parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptorsMol. Psychiatry3(2),123-134(1998)
Seeman, P., Corbett, R., and Van Tol, H.H.Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4 receptorsNeuropsychopharmacology16(2),93-110(1997)
Kroeze, W.K., Hufeisen, S.J., Popadak, B.A., et al.H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugsNeuropsychopharmacology28(3),519-526(2003)
Terry, A.V., Jr., Warner, S.E., Vandenhuerk, L., et al.Negative effects of chronic oral chlorpromazine and olanzapine treatment on the performance of tasks designed to assess spatial learning and working memory in ratsNeuroscience156(4),1005-1016(2008)
Gylys, J.A., Doran, K.M., and Buyniski, J.P.Antagonism of cisplatin induced emesis in the dogRes. Commun. Chem. Pathol. Pharmacol.23(1),61-68(1979)
