Alverine citrate
Cat. No.：YN321520
| 产品名称: | Alverine citrate |
| CAS No.: | 5560-59-8 |
| Chemical Name: | N-ethyl-N-(3-phenylpropyl)-benzenepropanamine, mono-2-hydroxy-1,2,3-propanetricarboxylate |
| Synonyms: | NSC 35459 |
| 分子量: | 473.56 |
| 分子式: | C₂₆H₃₅NO₇ |
| SMILES: | CCN(CCCC1=CC=CC=C1)CCCC2=CC=CC=C2.O=C(CC(C(O)=O)(O)CC(O)=O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Alverine citrate 是5-HT1A受体的一个拮抗剂，其IC50值为101 nM。 |
| IC50和靶点: | [{name:"5-HT1A Receptor:101 nM (IC50)"}] |
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Hayase, M., Hashitani, H., Suzuki, H., et al.Evolving mechanisms of action of alverine citrate on phasic smooth musclesBr. J. Pharmacol.152(8),1228-1238(2007)
Bouvier, M., Grimaud, J.C., Abysique, A., et al.Effects of alverine on the spontaneous electrical activity and nervous control of the proximal colon of the rabbitGastroenterol. Clin. Biol.16(4),334-338(1992)
Coelho, A.-M., Jacob, L., Fioramonti, J., et al.Rectal antinociceptive properties of alverine citrate are linked to antagonism at the 5-HT1A receptor subtypeJ. Pharm. Pharmacol.53(10),1419-1426(2001)
