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Thioridazine hydrochloride

Cat. No.:YN321589

  • CAS No. :130-61-0

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    • 产品名称: Thioridazine hydrochloride
      CAS No.: 130-61-0
      Chemical Name: 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine, monohydrochloride
      Synonyms:Aldazine, Mellaril
      分子量:407.04
      分子式:C₂₁H₂₇ClN₂S₂
      SMILES:CSC(C=C1N2CCC3N(C)CCCC3)=CC=C1SC4=C2C=CC=C4.[H]Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Thioridazine hydrochloride 是一种用于精神类疾病研究的化合物, 如精神分裂症, 具有多巴胺 D4 受体选择性和 5-羟色胺拮抗作用。
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    • Kroeze, W.K., Hufeisen, S.J., Popadak, B.A., et al.H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugsNeuropsychopharmacology28(3),519-526(2003)

      Tschanz, J.T., and Rebec, G.V.Atypical antipsychotic drugs block selective components of amphetamine-induced stereotypyPharmacol. Biochem. Behav.31(3),519-522(1988)

      Ishida-Tokuda, K., Ohno, Y., Sakamoto, H., et al.Evaluation of perospirone (SM-9018), a novel serotonin-2 and dopamine-2 receptor antagonist, and other antipsychotics in the conditioned fear stress-induced freezing behavior model in ratsJpn. J. Pharmacol.72(2),119-126(1996)

      Amaral, L.Thioridazine: An old neuroleptic effective against totally drug resistant tuberculosisActa Med. Port.25(2),118-121(2012)

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