Spiperone hydrochloride
Cat. No.:YN321649
产品名称: | Spiperone hydrochloride |
CAS No.: | 2022-29-9 |
Chemical Name: | |
Synonyms: | Spiroperidol hydrochloride |
分子量: | 431.93 |
分子式: | C₂₃H₂₇ClFN₃O₂ |
SMILES: | O=C1NCN(C2=CC=CC=C2)C13CCN(CCCC(C4=CC=C(F)C=C4)=O)CC3.[H]Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Spiperone hydrochloride (Spiroperidol hydrochloride) 是一种选择性的多巴胺D2受体 (D2,D3,D4,D1和 D5受体的Ki值分别为 0.06 nM,0.6 nM,0.08 nM,~350 nM,~3500 nM) 和5-HT2A/5-HT1A受体 (Ki为1 nM/49 nM) 拮抗剂。Spiperone hydrochloride 也是一种选择性的 α1B-肾上腺素受体 (α1B-adrenoceptor) 拮抗剂。Spiperone hydroc |
IC50和靶点: | [{name:"D2 Receptor:0.06 nM (Ki)"},{name: "D1 Receptor:~350 nM (Ki)"},{name: "D3 Receptor:0.6 nM (Ki)"},{name: "D4 Receptor:0.08 nM (Ki)"},{name: "D5 Receptor:~3500 nM (Ki)"},{name: "5-HT2A Receptor:1 nM (Ki)"},{name: "5-HT1A Receptor:49 nM (Ki)'}, 'α1B-adrenoceptor', 'Calcium-activated chloride channel'] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |