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Alprenolol

Cat. No.:YN321662

  • CAS No. :13655-52-2

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    • 参考文献
    • 产品名称: Alprenolol
      CAS No.: 13655-52-2
      Chemical Name: 1-[(1-methylethyl)amino]-3-[2-(2-propen-1-yl)phenoxy]-2-propanol
      Synonyms:阿普洛尔; (RS)
      分子量:249.35
      分子式:C₁₅H₂₃NO₂
      SMILES:OC(COC1=CC=CC=C1CC=C)CNC(C)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Alprenolol是一个非选择性的beta阻断剂,也是5-HT1A受体的拮抗剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Baker, J.G.The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptorsBr. J. Pharmacol.144(3),317-322(2005)

      Langlois, M., Brémont, B., Rousselle, D., et al.Structural analysis by the comparative molecular field analysis method of the affinity of β-adrenoreceptor blocking agents for 5-HT1A and 5-HT1B receptorsEur. J. Pharmacol.244(1),77-87(1993)

      Costain, D.W., and Green, A.R.β-Adrenoceptor antagonists inhibit the behavioural responses of rats to increased brain 5-hydroxytryptamineBr. J. Pharmacol.64(2),193-200(1978)

      Bond, R.A., Leff, P., Johnson, T.D., et al.Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptorNature374(6519),272-276(1995)

      Miyazaki, Y., Ishikawa, T., Kamatari, Y.O., et al.Identification of alprenolol hydrochloride as an anti-prion compound using surface plasmon resonance imagingMol. Neurobiol.,(2018)

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