Nuciferine
Cat. No.：YN321705
| 产品名称: | Nuciferine |
| CAS No.: | 475-83-2 |
| Chemical Name: | 5,6,6aR,7-tetrahydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline |
| Synonyms: | 荷叶碱 |
| 分子量: | 295.38 |
| 分子式: | C₁₉H₂₁NO₂ |
| SMILES: | CN1CCC2=CC(OC)=C(OC)C3=C2[C@@]1([H])CC4=CC=CC=C34 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nuciferine 是一种5-HT2A，5-HT2C和5-HT2B拮抗剂，IC50分别为 478 nM，131 nM 和 1 μM；也是5-HT7的反向激动剂，IC50为 150 nM。 |
| IC50和靶点: | [{name:"5-HT2C Receptor:131 nM (IC50)"},{name: "5-HT7 Receptor:150 nM (IC50)"},{name: "5-HT2A Receptor:478 nM (IC50)"},{name: "5-HT2B Receptor:1 μM (IC50)"},{name: "5-HT6 Receptor:700 nM (EC50)"},{name: "5-HT1A Receptor:3.2 μM (EC50)"},{name: "D2 Receptor:64 nM (EC50)"},{name: "D4 Receptor:2 μM (EC50)"},{name: "D5 Receptor:2.6 μM (EC50)"}] |
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Bhattacharya, S.K., Bose, R., Ghosh, P., et al.Psychopharmacological studies on (–)-nuciferine and its Hofmann degradation product atherospermininePsychopharmacology (Berl.)59(1),29-33(1978)
Holt, A.K., Poklis, J.L., and Peace, M.R.A retrospective analysis of chemical constituents in regulated and unregulated e-cigarette liquidsFront. Chem.9,752342(2021)
