Puerarin
Cat. No.：YN321711
CAS No. ：3681-99-0
| 产品名称: | Puerarin |
| CAS No.: | 3681-99-0 |
| Chemical Name: | 8-β-D-glucopyranosyl-7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Synonyms: | 葛根素 |
| 分子量: | 416.38 |
| 分子式: | C₂₁H₂₀O₉ |
| SMILES: | O=C1C(C2=CC=C(O)C=C2)=COC3=C([C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)C(O)=CC=C13 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 葛根素是从葛根中提取的异黄酮，是5-HT2C受体拮抗剂。 |
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Choo, M.K., Park, E.K., Yoon, H.K., et al.Antithrombotic and antiallergic activities of daidzein, a metabolite of puerarin and daidzin produced by human intestinal microfloraBiol. Pharm. Bull.25(10),1328-1332(2002)
Jin, J.S., Nishihata, T., Kakiuchi, N., et al.Biotransformation of C-glucosylisoflavone puerarin to estrogenic (3S)-equol in co-culture of two human intestinal bacteriaBiol. Pharm. Bull.31(8),1621-1625(2008)
Nakamura, K., Nishihata, T., Jin, J.S., et al.The C-glucosyl bond of puerarin was cleaved hydrolytically by a human intestinal bacterium strain PUE to yield its aglycone daidzein and an intact glucoseChem. Pharm. Bull. (Tokyo)59(1),23-27(2011)
Overstreet, D.H., Kralic, J.E., Morrow, A.L., et al.NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonistsPharmacol. Biochem. Behav.75(3),619-625(2003)
Chueh, F.S., Chang, C.P., Chio, C.C., et al.Puerarin acts through brain serotonergic mechanisms to induce thermal effectsJ. Pharmacol. Sci.96,420-427(2004)
Hu, W., Yang, X., Zhe, C., et al.Puerarin inhibits iNOS, COX-2 and CRP expression via suppression of NF-κB activation in LPS-induced RAW264.7 macrophage cellsPharmacol. Rep.63,781-789(2011)
