Jatrorrhizine
Cat. No.：YN321731
| 产品名称: | Jatrorrhizine |
| CAS No.: | 3621-38-3 |
| Chemical Name: | |
| Synonyms: | neprotin, Yatrorizine |
| 分子量: | 338.38 |
| 分子式: | C₂₀H₂₀NO₄+ |
| SMILES: | COC1=C(OC)C2=C[N+]3=C(C4=CC(OC)=C(O)C=C4CC3)C=C2C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Jatrorrhizine是从黄连中分离得到的生物碱，具有神经保护、抗菌、抗疟原虫和抗氧化活性。Jatrorrhizine是有效的，具有口服活性的乙酰胆碱酯酶 (AChE) (IC50=872 nM) 的抑制剂，是对 BuChE 的选择性为 115 倍。Jatrorrhizine 通过抑制 uptake-2 transporter 的活性减少血清素 (5-HT) 和去甲肾上腺素 (NE) 的摄取。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
