A1AR antagonist 3
Cat. No.：YN322126
| 产品名称: | A1AR antagonist 3 |
| CAS No.: | 1018830-99-3 |
| Chemical Name: | [2-amino-4-[3-(trifluoromethyl)phenyl]-3-thienyl]phenyl-methanone |
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| 分子量: | 347.3552296 |
| 分子式: | C18H12F3NOS |
| SMILES: | NC1=C(C(C2=CC=CC=C2)=O)C(C3=CC(C(F)(F)F)=CC=C3)=CS1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | VCP171 是一种有效的腺苷 A1 受体 (A1R)正向变构调节剂。VCP171 能有效降低神经性疼痛模型 Lamina II 的兴奋性突触电流。VCP171 可用于神经性疼痛的研究。 |
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Aurelio, L., Figler, H., Flynn, B.L., et al.5-Substituted 2-aminothiophenes as A1 adenosine receptor allosteric enhancersBioorg. Med. Chem.16(3),1319-1327(2008)
Imlach, W.L., Bhola, R.F., May, L.T., et al.A positive allosteric modulator of the adenosine A1 receptor selectively inhibits primary afferent synaptic transmission in a neuropathic pain modelMol. Pharm.88(3),460-468(2015)
