Sumatriptan
Cat. No.：YN322132
CAS No. ：103628-46-2
| 产品名称: | Sumatriptan |
| CAS No.: | 103628-46-2 |
| Chemical Name: | 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide; 3-[2-(Dimethylamino)ethyl]-N-methylindolyl-5-methanesulfonamide; GR 43175; GR 43175X; Zelrix |
| Synonyms: | GR 43175 free base |
| 分子量: | 295.4 |
| 分子式: | C14H21N3O2S |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sumatriptan (GR 43175 free base) 是一种具有口服活性的5-HT1受体激动剂，对5-HT1D、5-HT1B和5-HT1A受体的Ki分别为 17 nM、27 nM 和 100 nM。Sumatriptan 可用于偏头痛研究。 |
| IC50和靶点: | [{name:"5-HT1A Receptor:100 nM (Ki)"},{name: "5-HT1B Receptor:27 nM (Ki)"},{name: "5-HT1D Receptor:17 nM (Ki)"}] |
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| Solvent & Solubility: |
Humphrey, P.P.A., et al.: Brit. J. Pharmacol., 94, 1123 (1988)
Doenicke, A., et al.: Lancet 1, 1309 (1988)
