U-75302
Cat. No.:YN322178
产品名称: | U-75302 |
CAS No.: | 119477-85-9 |
Chemical Name: | 6-(6-(3R-hydroxy-1E,5Z-undecadien-1-yl)-2-pyridinyl)-1,5S-hexanediol |
Synonyms: | |
分子量: | 361.5 |
分子式: | C22H35NO3 |
SMILES: | OCCCC[C@H](O)CC1=NC(/C=C/[C@H](O)C/C=C\CCCCC)=CC=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | U-75302 是一种有效的leukotriene B4抑制剂。U-75302 是一种吡啶类似物。U-75302 具有研究炎症性疾病的潜力。 |
IC50和靶点: | |
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Falcone, R.C., and Aharony, D.Modulation of ligand binding to leukotriene B4 receptors on guinea pig lung membranes by sulfhydryl modifying reagentsJ. Pharmacol. Exp. Ther.255,565-571(1990)
Lin, A.H., Morris, J., Wishka, D.G., et al.Novel molecules that antagonize leukotriene B4 binding to neutrophilsAnn. N.Y. Acad. Sci.524,196-200(1988)
Wang, S., Gustafson, E., Pang, L., et al.A novel hepatointestinal leukotriene B4 receptorJ. Biol. Chem.275(52),40686-40694(2000)