TUG-469
Cat. No.：YN322200
CAS No. ：1236109-67-3
| 产品名称: | TUG-469 |
| CAS No.: | 1236109-67-3 |
| Chemical Name: | 4-[[(2'-Methyl[1,1'-biphenyl]-3-yl)methyl]amino]benzenepropanoic Acid; 3-(4-(((2'-Methyl-[1,1'-biphenyl]-3-yl)methyl)amino)phenyl)propanoic Acid |
| Synonyms: | |
| 分子量: | 345.43 |
| 分子式: | C23H23NO2 |
| SMILES: | O=C(CCC1=CC=C(C=C1)NCC2=CC(C3=CC=CC=C3C)=CC=C2)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TUG-469 是选择性的游离脂肪酸受体 1 (FFA1/GPR40) 激动剂，EC50值为 19 nM。TUG-469 对 FFA1 的选择性是 FFA4 的 200 倍。TUG-469 显著改善糖尿病早期小鼠的糖耐量。TUG-469 可用于糖尿病的研究。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Urban, C., et. al.: Naunyn-Schmiedeberg's Arch. Pharm., 386, 1021 (2013)
