MK-8318
Cat. No.：YN322254
| 产品名称: | MK-8318 |
| CAS No.: | 1416581-40-2 |
| Chemical Name: | |
| Synonyms: | MK8318 |
| 分子量: | 534.5 |
| 分子式: | C27H26F4N2O5 |
| SMILES: | C(O)(=O)CCC(N(C1CC1)[C@@H]1C2=C(N(C(=O)C3=CC=C(OC(F)(F)F)C=C3)[C@@]([H])3CCC[C@@]31[H])C=CC(F)=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MK-8318 是一种有效的选择性CRTh2受体拮抗剂，Ki为 5.0 nM。 |
| IC50和靶点: | [{name:"DP:5.0 nM (Ki)"},{name: "β-arrestin:3.5 nM (IC50)"},{name: "cAMP:8.0 nM (IC50)"},{name: "CYP3A4:50 μM (IC50)"},{name: "CYP2C9:50 μM (IC50)"},{name: "CYP2D6:50 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
