Leelamine
Cat. No.：YN322266
| 产品名称: | Leelamine |
| CAS No.: | 1446-61-3 |
| Chemical Name: | 1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine |
| Synonyms: | |
| 分子量: | 285.5 |
| 分子式: | C20H31N |
| SMILES: | CC(C)C(C=C1)=CC2=C1[C@]3(C)[C@](CC2)([H])[C@@](CN)(C)CCC3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Leelamine 是大麻素受体CB1和CB2的弱激动剂。Leelamine 也可以抑制丙酮酸脱氢酶激酶 (PDK)。Leelamine 具有抗肿瘤活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Aicher, T.D., Damon, R.E., Koletar, J., et al.Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK)Bioorg. Med. Chem. Lett.9(15),2223-2228(1999)
Yoshida, M., Kawasaki, A., Yukimoto, M., et al.Detection of the effects of fungicides on the cell membrane by proton nuclear magnetic resonance spectroscopyPest. Biochem. Phys.38(2),172-177(1990)
Kuzu, O.F., Gowda, R., Sharma, A., et al.Leelamine mediates cancer cell death through inhibition of intracellular cholesterol transportMol. Cancer Ther.13(7),1690-1703(2014)
