CYM-5520
Cat. No.：YN322268
CAS No. ：1449747-00-5
| 产品名称: | CYM-5520 |
| CAS No.: | 1449747-00-5 |
| Chemical Name: | 1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-1,6-dihydro-6-oxo-3-pyridinecarbonitrile |
| Synonyms: | |
| 分子量: | 345.4 |
| 分子式: | C21H19N3O2 |
| SMILES: | O=C1C=CC(C#N)=CN1CC(C2=C(C)N(CC3=CC=CC=C3)C(C)=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CYM-5520 是一种选择性的变构鞘氨醇 1-磷酸受体 2 (S1PR2) 激动剂，EC50为 480 nM。CYM-5520 不激活 S1PR1、S1PR3、S1PR4 和S1PR5受体。CYM-5520 可以在S1PR2受体中与 S1P 结合。CYM-5520 可用于骨质疏松症研究。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Satsu, H., Schaeffer, M.T., Guerrero, M., et al.A sphingosine 1-phosphate receptor 2 selective allosteric agonistBioorg. Med. Chem.21(17),5373-5382(2013)
