Bupranolol
Cat. No.:YN322272
产品名称: | Bupranolol |
CAS No.: | 14556-46-8 |
Chemical Name: | 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-2-propanol |
Synonyms: | |
分子量: | 271.78272 |
分子式: | C14H22ClNO2 |
SMILES: | ClC1=CC=C(C)C=C1OCC(CNC(C)(C)C)O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Bupranolol 是一种口服活性、竞争性和非选择性β-adrenoceptor拮抗剂,无固有的拟交感神经活性。 |
IC50和靶点: | |
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Wellstein, A., Küppers, H., Pitschner, H.F., et al.Transdermal delivery of bupranolol: Pharmacodynamics and beta-adrenoceptor occupancyEur. J. Clin. Pharmacol.31(4),419-422(1986)
Malinowska, B., Kieć-Kononowicz, K., Flau, K., et al.Atypical cardiostimulant β-adrenoceptor in the rat heart: Stereoselective antagonism by bupranolol but lack of effect by some bupranolol analoguesBr. J. Pharmacol.139(8),1548-1554(2003)