SC-51322
Cat. No.：YN322273
| 产品名称: | SC-51322 |
| CAS No.: | 146032-79-3 |
| Chemical Name: | 8-chloro-2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]hydrazide, dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid |
| Synonyms: | |
| 分子量: | 457.9 |
| 分子式: | C22H20ClN3O4S |
| SMILES: | ClC(C=C1)=CC2=C1OC3=CC=CC=C3CN2C(NNC(CCSCC4=CC=CO4)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SC-51322 是一种有效和选择性的前列腺素 E2 (PGE2) 受体 (EP1) 拮抗剂，pA2为 8.1。SC-51322 具有镇痛作用。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Hallinan, E.A., Hagen, T.J., Tsymbalov, S., et al.Aminoacetyl moiety as a potential surrogate for diacylhydrazine group of SC-51089, a potent PGE2 antagonist, and its analogsJ. Med. Chem.39,609-613(1996)
Foudi, N., Kotelevets, L., Louedec, L., et al.Vasorelaxation induced by prostaglandin E2 in human pulmonary vein: Role of the EP4 receptor subtypeBr. J. Pharmacol.154,1631-1639(2008)
