Scopolamine butylbromide
Cat. No.:YN322281
产品名称: | Scopolamine butylbromide |
CAS No.: | 149-64-4 |
Chemical Name: | (1α,2β,4β,5α,7β)-9-butyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane, monobromide |
Synonyms: | Hyoscine butylbromide; (- |
分子量: | 440.37124 |
分子式: | C21H30NO4 • Br |
SMILES: | O=C(O[C@@H]1C[C@@H]([N@+]2(CCCC)C)[C@H]3O[C@H]3[C@@H]2C1)[C@H](CO)C4=CC=CC=C4.[Br-] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Scopolamine butylbromide是毒蕈碱乙酰胆碱受体(mAChR)拮抗剂,IC50为55.3 nM。 |
IC50和靶点: | |
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Bauer, R., and Wick, H.Comparative spasmolytic potencies of atropine sulphate and N-butyl hyoscine bromide following intravenous injection, injection into a mesenteric vein, and intraduodenal instillationJ. Pharm. Pharmacol.21(10),706-708(1969)
Sagrada, A., Schiavone, A., Cefalá, A., et al.N-butyl hyoscine exerts local spasmolytic effect in the small and large bowel of the conscious dogArch. Int. Pharmacodyn. Ther.287(2),237-247(1987)