SR 49059
Cat. No.:YN322284
CAS No. :150375-75-0
产品名称: | SR 49059 |
CAS No.: | 150375-75-0 |
Chemical Name: | 1-[[(2R,3S)-5-chloro-3-(2-chlorophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-hydroxy-1H-indol-2-yl]carbonyl]-2-pyrrolidinecarboxamide |
Synonyms: | 2-Pyrrolidinecarboxamide,1-[[(2R,3S)-5-chloro-3-(2-chlorophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-hydroxy-1H-indol-2-yl]carbonyl]-,(2S)-;2-Pyrrolidinecarboxamide,1-[[(2R,3S)-5-chloro-3-(2-chlorophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3- |
分子量: | 620.5 |
分子式: | C28H27Cl2N3O7S |
SMILES: | ClC1=CC=CC=C1[C@]2(O)[C@H](C(N3CCC[C@H]3C(N)=O)=O)N(S(C4=CC=C(OC)C(OC)=C4)(=O)=O)C5=CC=C(Cl)C=C52 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SR 49059 (SR-49059) 是一种有效的、具有口服活性的、选择性的vasopressin V1a拮抗剂,Ki值为 1.4 nM. |
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Serradiel-Le Gal, C., Wagnon, J., Garcia, C., et al.Biochemical and pharmacological properties of SR 49059, a new, potent, nonpeptide antagonist of rat and human vasopressin V1a receptorsJ. Clin. Invest.92(1),224-231(1993)
Thibonnier, M., Conarty, D.M., Preston, J.A., et al.Molecular pharmacology of human vasopressin receptorsVasopressin and Oxytocin1,251-276(1998)