GT-2016
Cat. No.：YN322288
| 产品名称: | GT-2016 |
| CAS No.: | 152241-24-2 |
| Chemical Name: | 5-cyclohexyl-1-[4-(1H-imidazol-5-yl)-1-piperidinyl]-1-pentanone |
| Synonyms: | |
| 分子量: | 317.5 |
| 分子式: | C19H31N3O |
| SMILES: | O=C(CCCCC1CCCCC1)N2CCC(C3=CN=CN3)CC2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GT-2016 是一种有效的、选择性的可穿过血脑屏障的组胺H3受体拮抗剂，Ki为 43.8 nM。GT-2016 对 H1 和 H2 受体具有选择性，并对组胺甲基转移酶无活性。 |
| IC50和靶点: | [{name:"H3 Receptor:43.8 nM (Ki)"}] |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Tedford, C.E., Yates, S.L., Pawlowski, G.P., et al.Pharmacological characterization of GT-2016, a non-thiourea-containing histamine H3 receptor antagonist: In vitro and in vivo studiesJ. Pharmacol. Exp. Ther.275(2),598-604(1995)
