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DC-Chol hydrochloride

Cat. No.:YN380350

  • CAS No. :166023-21-8

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    • 参考文献
    • 产品名称: DC-Chol hydrochloride
      CAS No.: 166023-21-8
      Chemical Name: (3β)-cholest-5-en-3-ol 3-[N-[2-(dimethylamino)ethyl]carbamate], monohydrochloride
      Synonyms:DC-Cholesterol hydrochloride
      分子量:537.3
      分子式:C32H56N2O2 • HCl
      SMILES:CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(NCCN(C)C)=O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C.Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: DC-Chol hydrochloride 在适当的实验条件下能抑制 Aβ40 纤维的形成。DC-Chol hydrochloride 以剂量依赖性的方式强烈抑制氧化hCT的淀粉样蛋白形成。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Michel, T., Luft, D., Abraham, M.K., et al.Cationic nanoliposomes meet mRNA: Efficient delivery of modified mRNA using hemocompatible and stable vectors for therapeutic applicationsMol. Ther. Nucleic Acids8,459-468(2017)

      Gao, J., Sun, J., Li, H., et al.Lyophilized HER2-specific PEGylated immunoliposomes for active siRNA gene silencingBiomaterials31(9),2655-2664(2010)

      Zhang, R., Wang, S.B., Chen, A.Z., et al.Codelivery of paclitaxel and small interfering RNA by octadecyl quaternized carboxymethyl chitosan-modified cationic liposome for combined cancer therapyJ. Biomater. Appl.30(3),351-360(2015)

      Men, Y., Wang, X.X., Li, R.J., et al.The efficacy of mitochondrial targeting antiresistant epirubicin liposomes in treating resistant leukemia in animalsInt. J. Nanomedicine6,3125-3137(2011)

      Xing, X., Liu, V., Xia, W., et al.Safety studies of the intraperitoneal injection of E1A-liposome complex in miceGene Ther.4(3),238-243(1997)

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