UPF-523
Cat. No.：YN322320
| 产品名称: | UPF-523 |
| CAS No.: | 168560-79-0 |
| Chemical Name: | 1-Amino-2,3-dihydro-1H-indene-1,5-dicarboxylic Acid; 1-Aminoindan-1,5-dicarboxylic Acid; UPF 523 |
| Synonyms: | AIDA |
| 分子量: | 221.21 |
| 分子式: | C11H11NO4 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | UPF-523 (AIDA) 是一种刚性 (羧基苯基) 甘氨酸衍生物，是I组代谢型谷氨酸受体(mGlu1a)的高效选择性拮抗剂，IC50值为 214 μM。但 UPF-523 对 II 组 (mGlu2)，III 组 (mGlu4) 受体和离子型谷氨酸受体没有影响。UPF-523 具有研究急性关节炎的潜力。 |
| IC50和靶点: | [{name:"mGluR1a:214 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Chen, T. et al.: Cell Death & Disease (2020), 11(1), 4
