Ro 60-0175
Cat. No.：YN322325
| 产品名称: | Ro 60-0175 |
| CAS No.: | 169675-09-6 |
| Chemical Name: | (ɑS)-6-chloro-5-fluoro-ɑ-methyl-1H-indole-1-ethanamine, (2E)-2-butenedioate |
| Synonyms: | Ro 60-0175 fumarate|Ro 600175 fumarate |
| 分子量: | 342.8 |
| 分子式: | C11H12ClFN2 • C4H4O4 |
| SMILES: | N[C@@H](C)CN1C=CC2=CC(F)=C(Cl)C=C21.OC(/C=C/C(O)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ro60-0175 fumarate 是一种有效的选择性5-HT2C受体激动剂。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Porter, R.H.P., Benwell, K.R., Lamb, H., et al.Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cellsBr. J. Pharmacol.128(1),13-20(1999)
Martin, J.R., Bös, M., Jenck, F., et al.5-HT2C receptor agonists: Pharmacological characteristics and therapeutic potentialJ. Pharmacol. Exp. Ther.286(2),913-924(1998)
Damjanoska, K.J., Muma, N.A., Zhang, Y., et al.Neuroendocrine evidence that (S)-2-(chloro-5-fluoro-indol-l-yl)-1-methylethylamine fumarate (Ro 60-0175) is not a selective 5-hydroxytryptamine2C receptor agonistJ. Pharmacol. Exp. Ther.304(3),1209-1216(2003)
